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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3GLB1
All Species:
14.55
Human Site:
S254
Identified Species:
32
UniProt:
Q9Y371
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y371
NP_057093.1
365
40796
S254
D
L
Q
K
Q
L
G
S
F
P
S
N
Y
L
S
Chimpanzee
Pan troglodytes
XP_520303
400
44342
T289
Q
G
A
I
F
P
G
T
F
V
G
T
T
E
P
Rhesus Macaque
Macaca mulatta
XP_001109639
365
40748
S254
D
L
Q
K
Q
L
G
S
F
P
S
N
Y
L
S
Dog
Lupus familis
XP_855325
448
50224
G337
L
D
L
Q
K
Q
L
G
S
F
P
S
S
Y
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9JK48
365
40837
S254
D
L
Q
K
Q
L
G
S
F
P
S
N
Y
L
S
Rat
Rattus norvegicus
Q6AYE2
365
40769
S254
D
L
Q
K
Q
L
G
S
F
P
S
N
Y
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508524
364
40538
F253
L
Q
K
Q
L
G
S
F
P
T
T
F
L
A
N
Chicken
Gallus gallus
Q5ZIR1
366
40777
F255
L
Q
K
Q
L
G
S
F
P
S
T
F
L
S
N
Frog
Xenopus laevis
Q6GM14
376
42749
L266
F
L
Q
K
E
R
S
L
P
E
S
G
S
V
S
Zebra Danio
Brachydanio rerio
NP_001017617
360
40174
N251
D
L
Q
K
Q
L
G
N
F
P
S
A
F
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001191773
357
39709
Q247
S
Q
T
M
T
E
L
Q
Q
Q
L
G
N
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.5
99.7
74.7
N.A.
95.8
94.7
N.A.
87.6
86.8
20.4
75.3
N.A.
N.A.
N.A.
N.A.
55.3
Protein Similarity:
100
75.5
99.7
78.1
N.A.
96.9
96.7
N.A.
92.8
92
33.7
84.6
N.A.
N.A.
N.A.
N.A.
71.7
P-Site Identity:
100
13.3
100
0
N.A.
100
93.3
N.A.
0
0
33.3
73.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
100
20
N.A.
100
100
N.A.
26.6
26.6
46.6
86.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
46
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
10
0
0
0
10
0
0
0
10
0
% E
% Phe:
10
0
0
0
10
0
0
19
55
10
0
19
10
0
0
% F
% Gly:
0
10
0
0
0
19
55
10
0
0
10
19
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
19
55
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
28
55
10
0
19
46
19
10
0
0
10
0
19
28
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
37
10
0
19
% N
% Pro:
0
0
0
0
0
10
0
0
28
46
10
0
0
0
19
% P
% Gln:
10
28
55
28
46
10
0
10
10
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
28
37
10
10
55
10
19
10
55
% S
% Thr:
0
0
10
0
10
0
0
10
0
10
19
10
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
37
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _